The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with ...

Cyanobacteria—ancient microbes that oxygenated Earth and made complex life possible—are still revealing surprises billions of years later. Scientists have now discovered that a molecular system once ...

DNA is often called the blueprint of life, but what does that really mean? Elizabeth Worthey, Ph.D., associate professor, Department of Genetics in the Heersink School of Medicine, explains everything ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...

“The laws of inheritance are quite unknown,” Charles Darwin acknowledged in 1859. The discovery of DNA’s shape altered how we conceived of life itself. The X-ray crystallography by Rosalind Franklin ...

A simulated cell in the early stages of division. Left half shows cytoplasm (blue cubes), mRNA degradation machinery molecules (pink), and sugar transporters (brown). Right half adds the membrane ...

DNA replication in eukaryotic cells is a highly coordinated, multi-step process that ensures precise duplication of the genome prior to cell division. In late mitosis and early G1 phase, the Origin ...