The opioid epidemic has claimed more than half a million lives in the U.S. since 1999, about three-quarters of them men, according to the National Institutes of Health. Although men's disproportionate ...

A new synthetic opioid designed to relieve pain could hold promise for replacing addictive painkillers like morphine or fentanyl in patients, a study in lab rats suggests. The research hints that the ...

Could sex hormones explain the difference in opioid use and misuse between genders? Since 1999, the American opioid epidemic has killed more than half a million people, and according to the National ...

Most people who misuse opioids take the drugs to relieve pain, but data suggest that men are more likely to misuse and overdose on opioids than women, even though they suffer less chronic pain.

While the opioid epidemic is one of the most urgent public health emergencies facing the U.S., new therapeutic approaches for treating the underlying substance use disorder have lagged far behind.

While opioids are incredibly powerful pain management tools, they can also be highly addictive. Since 2013, the rate of deaths from an overdose due to synthetic opioids, like fentanyl, has steadily ...

Millions of Americans are taking a prescription opioid to help ease chronic pain, and many would like to taper their dosage New research finds that collaboration between patient and doctor works best ...

Brain cells (magenta) in the reward center of a rat’s brain release dopamine in response to opioids. According to a new study by WashU Medicine researchers, male and female rats with a chronic pain ...