Ongoing work in functional annotations of genomes has generated rich datasets. We propose a method to link extensive functional annotations to genotype-to-phenotype associations. This method ranks ...
Fluid shear stress mediates vascular homeostasis by regulating gene expression in endothelial cells (ECs). Using single-cell RNA sequencing, this study provides a comprehensive perspective of ...
Copyright: © 2023 The Author(s). Published by Elsevier B.V. Two new AD/dementia GWAS have dramatically expanded the sample sizes and the number of disease ...
Re-organization of the software package => user-friendly version with Docker. Speed up file reading in R with data.table. Fix bugs in hg38 annotation. Default option "-td" changed to FALSE. Output ...
Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Optimization ...
If you use this package for your research, please cite: Ho, S. Y. W., Duchêne, S., Duchêne, D. (2015) Simulating and detecting autocorrelation of molecular evolutionary rates among lineages. 15(4) 689 ...
Metagenomic studies unravel details about the taxonomic composition and the functions performed by microbial communities. As a complete metagenomic analysis requires different tools for different ...
The development of innovative single-cell technologies has allowed the high-dimensional transcriptomic and proteomic profiling of individual blood and tissue cells. Recent single-cell studies revealed ...
jSouth Africa MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa kDepartment of Clinical, ...